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Bipolar Disorder - What Science Has To Say

Bipolar Disorder

<p>Despite bipolar disorder being increasingly popular in many young adults and full adults, there is not a whole lot of advanced study in understanding where it comes from, how it impacts patients, and what can be done about it.&nbsp; For this reason, it is important to take it apart and take note of just what we do understand.&nbsp; This leads experts to understand what must still be learned from further study.</p> <p>What bipolar disorder signifies</p> <p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Detailed study on the science of bipolar disorder in patients shows that research and a full comprehension of this mental disorder is far from guaranteed.&nbsp; The most recent study shows that bipolar disorder is thought to be part of a complex, multi-faceted biological issue.&nbsp; Instead of simple hormones, it involves various parts of the body&rsquo;s system.</p> <p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; This includes the noradrenergic system, the serotonergic system, the dopaminergic system, and the cholinergic system.&nbsp; These are all impacted by, and impact themselves, bipolar disorder.&nbsp;</p> <p>What experts know</p> <p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Bipolar disorder can fluctuate throughout a patient&#39;s life.&nbsp; Mood swings between manic and depressive episodes do tend to change in their severity, timing and even the physical reactions in the patient.&nbsp; Recent studies have clarified several details, including:</p> <ul> <li><strong>Neurotrophic and neuroprotective factors play a role:</strong> When it comes to understanding the role of these factors, there is thought to be a connection between gene depression and mood stabilizers.&nbsp; Since bipolar disorder is understood to be connected to gene sequences and interruptions of those sequences, this is an intriguing detail.&nbsp; Experts hope to understand how manipulating those factors can help when matching mood stabilizers for long-term treatment.</li> </ul> <ul> <li><strong>There is a neurobiological connection:</strong> More study is needed in the neuroanatomical study area, as many of the research results showed abnormalities specifically in the signal transduction.&nbsp; It is considered to be a nutritional dysfunction specific to the brain, and understanding how to compensate for that with medication can help ease symptoms and mood swings in patients.</li> </ul> <ul> <li><strong>The circadian rhythm is interrupted: </strong>Responsible for proper rest and repair, patients with bipolar disorder can have an interrupted rhythm, particular when in the middle of a depressive episode.&nbsp; This is a connection also found in those with major depressive disorder.&nbsp; When these genes are not functioning properly, there is an established connection between the two conditions.</li> </ul> <ul> <li><strong>The brain looks different:</strong> Similarly, there are documented abnormalities when it comes to both blood flow and metabolic rates.&nbsp; This is backed up further by a reduction in the overall CNS volume and cell number.</li> </ul> <p>What does this all mean?</p> <p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; While there is still a long way to go in understanding long-term mood stabilizers and the potential benefits for those living with bipolar disorder, the research is starting to show scientists and experts that there is an option to truly understand bipolar disorder from a biological perspective as well as symptom-based approach.&nbsp; It means that in the future, research will give experts the position of easier, better, and more targeted treatment for all those struggling with current shortcomings.</p> <p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Without question, there is still a long way to go in understanding bipolar disorder and how it impacts the brain and biological processes, but research is starting to give a guide and a focus to help make treatment possible as well as better, overall, for all those who are currently living with it.</p>